The image shows the text "DEAR BRIGHTLY" in bold, capital letters with a small star shape next to it.

Night Shift

Rx Face Serum
$66 Trial Offer
First-time trial 2-month supply
220 Reviews
A blue car is parked in a modern driveway surrounded by trees and plants.
Night Shift, our tailored retinoid serum, is the backbone of a great skincare routine. Proven to prevent and treat wrinkles, uneven skin tone, enlarged pores, and acne, it’s no wonder this dermatologist-tested super serum is making gains. Get your tailored prescription without leaving your house.
ADD TO CART
Free shipping
*At checkout, answer questions and upload photos of your skin for your provider to determine if a prescription is appropriate.

Tretinoin Prescription Online

First-time bottle lasts ~2 months. Refills last ~3 months and bill at $99/quarter. Change frequency or cancel anytime.
Enjoy the ease of a virtual dermatologist review and get your Tretinoin, a prescription strength retinoid online.
Bonus ingredient: Niacinamide, an anti-inflammatory healing compound that calms redness and boosts hydration.
AGING IS LIVING™

Anti-aging doesn't exist in our dictionary. We're pro-aging and here to do it better than ever. When you're comfortable in your skin, you're more confident in yourself. And when you're confident in yourself, you embrace that aging is living - a belief that shines from the skinside out. Get your tailored Tretinoin prescription online today.

GET TO KNOW NIGHT SHIFT

Night Shift is formulated with a powerful blend of Tretinoin, a prescription strength retinoid, and gentle, hydrating ingredients to transform your nightly skincare routine. Harnessing the dynamic duo of Tretinoin and Niacinamide, our tailored formula from skin experts is made for your unique skin. Our silky-smooth texture indulges your skin with every application.

TRETINOIN SERUM + NIACINAMIDE BENEFITS

Trust the science. Your Tretinoin prescription online is proven to prevent and treat wrinkles, pigmentation, uneven skin tone, enlarged pores, and acne. Its redness-reducing anti-inflammatory partner, niacinamide, reduces the appearance of big pores, prevents moisture loss and dehydration, and brightens the skin. Like every perfect match, they work together to reveal your best skin ever.

The power of retinoids.

A pie chart with sections for wealth distribution: 4% in the middle class, 0.7% in the top 5%, and 0.2% in the top 1%.
Retinoid stimulates the production of collagen, softening the appearance of fine lines and wrinkles. They also boost new blood vessels, which can give you a youthful rosy glow.
A pie chart divided into five segments, with a diagonal line across two segments. Two arrows point to these segments, labeled "internal" and "external.
Yes! Retinoids clear cellular debris around enlarged pores, making them appear smaller and keeping them cleaner.
A pie chart with three labeled sections: one large and light green, one medium and darker green, and one small in dark purple. Simple design with no numeric or text details visible.
Retinoids are a first-line defense for treating and preventing blackheads as they decrease comedones and their precursor, thereby decreasing non inflammatory and inflammatory acne.
A pie chart with three labeled sections: one large and light green, one medium and darker green, and one small in dark purple. Simple design with no numeric or text details visible.
Tough acne that hasn’t responded to your usual treatments may respond well to a topical tretinoin prescription online. Retinoids unclog pores, which means your skin will absorb creams more efficiently.
A pie chart showing various label positions, with annotations pointing to different sections around the yellow circle.
Since topical retinoids exfoliate the skin, they definitely aid in the natural elimination of milia. It also iImproves roughness by reducing the layer of dead skin cells and increasing glycosaminoglycan (GAG).
Pie chart showing four segments: 60% largest, 24% second, 12% third, and 4% smallest.
While not a cure-all for every type of hyperpigmentation, anti-inflammatory topical retinoids can improve pigmentation of freckles, melasma, sun spots and dark spots by dispersing melanin granules.
A close-up of a mound of yellow powder against a white background.

Tretinoin

This topical retinoid helps the skin by removing dead layers of skin and unclogging pores. Depending on your skin profile evaluation, your online Tretinoin prescription strengths can range from 0.015% to .089%
Close-up of water droplets on a smooth, reflective surface.

Niacinamide

Also called nicotinamide, this anti-aging NSAID is a form of B3 found in many common foods. It’s required for well functioning fats and sugars in the body and the maintenance of healthy cells.
Base: ST-Elastomer 10, Q7-9120 Silicone Fluid, EL-7040 Hydro Elastomer Blend, Vitamin E Acetate, Liquid, Polyglycerol-3 Diisostearique
Black square with no visible content.
ALCHOHOL FREE
A black square with nothing visible inside.
CRUELTY FREE
A blank black square image.
FRAGRANCE FREE
Black and white drawing of a muscular man in a dynamic pose, holding a large, ornate sword.
PARABEN FREE

As easy as 1-2-3.

Get a tailored solution from our dermatologist partners to match your unique skin profile – gentle enough for even the most sensitive skin.

STEP 1

Share your skin goals
No need for an in-person visit to the
dermatologist. In just a few minutes, share details about your skin and upload photos on our secure telehealth portal.

STEP 2

Our doctors tailor your formula
You are unique and your skin is too. A doctor will review your profile and tailor your derm-strength Night Shift serum to create a formula just for you.

STEP 3

Check in with your skin coach
Like any fitness routine, retinoids work best by starting out slowly. Your provider is available at any time to check in and assess your progress.

Night Shift for anyone and everyone.

Whether you have sensitive or dry skin, or whether you’re a retinoid rookie or not, our Board-certified doctors got you. Understanding that everyone's skin is different, they provide you with an appropriate strength of our tailored Tretinoin prescription for your specific skin type.

When your skin is ready, they’ll even upgrade your strength. At Dear Brightly we are committed to giving you a better overall retinoid experience.
Three people smiling, close together, against a plain background.

Start seeing results as early as 2 weeks.*

Practice makes progress! Start slowly, be patient, and watch your skin transform. Collagen isn’t built in a day, so we’ve made sure you’ve got the right routine for the journey. And we’re here to be your coach, teammate, and biggest fan – every step of the way.

*Individual Results May Vary
Close-up of a woman's face with blue eyes and freckles, showing a streak of sunscreen on her cheek, and her lips slightly closed in a neutral expression.
1-2 weeks
Brightens and reduces uneven skin tone.
Close-up of a person touching their cheek, showing smooth skin and a neutral expression.
2-4 weeks
Discoloration is improved.
A person with freckles gazes upward with a thoughtful expression, resting one hand on their face.
4-6 weeks
Brown spots diminish.
A person applies a skincare product to their cheek with a finger.
3-6 months
Reduced fine lines and wrinkles.
Person gently applying skincare product to their cheek with eyes closed.
6 months - 1 year
Clear, radiant skin

Complete your skincare fitness routine.

Our Derma Five products are designed for your healthiest skin. Developed by dermatologists, each of these products work in conjunction with Night Shift for optimal skin health.

Community Reviews

crossmenu linkedin facebook pinterest youtube rss twitter instagram facebook-blank rss-blank linkedin-blank pinterest youtube twitter instagram